Gastric pentadecapeptide BPC 157 promotes corneal epithelial defects healing in rats
Lazić et al./PubMed/2005
Why It Matters
This caught my attention because BPC-157 gets a lot of hype in biohacking circles, but most human data is sparse. This is a small rat study from 2005 showing faster corneal healing with eye drops — interesting mechanistically, but we're talking about 48 rats with induced eye injuries. Not remotely close to evidence for human use, and definitely not something to experiment with in your own eyes. Worth knowing about for understanding BPC-157's wound healing mechanisms, but that's it.
Key Findings
- Rats treated with BPC-157 eye drops (microgram and nanogram doses) showed significantly faster corneal healing compared to water-treated controls
- Complete wound closure occurred at 40 hours (microgram dose) or 48 hours (nanogram dose) in treated rats, while control wounds remained present at 48 hours
- Effects were dose-dependent, with both microgram and nanogram concentrations showing benefit but the picogram dose showing no significant effect
- Study used total corneal epithelium debridement (complete removal of surface layer) as the injury model, with treatments applied every 8 hours
Read the Paper↗PMID: 16117343